prof. Michail Daniilidis
Professor of Internal Medicine
Clinical & Reproductive Immunology A.U.TH.
Immunological Research and Immunotherapy Center
The only immunological medical center founded by a Professor of Clinical Immunology
– Miscarriages, unsuccessful embryo transfers
(repeated implantation failures)
– Immunology of Reproduction
– Immunological & Autoimmune diseases
– Immunological causes of Hypersensitivity – Allergies
– “Immune adequacy” check (immunological check up)
What is immunology?
Immunology is a scientific discipline that focuses on the investigation of the cellular, molecular, and organ-based mechanisms involved in antigen recognition and processing, as well as the subsequent interactions and responses among these components. This field encompasses the analysis of both the beneficial and adverse outcomes of the immune response, including strategies for its suppression or augmentation. A primary function of the immune system is to provide protection against pathogens or molecules identified as alien or “non-self,” through the activation of innate followed by adaptive immune mechanisms. Furthermore, immunology includes the study of immune system-mediated disease prevention via appropriate vaccination strategies. However, it also addresses the detrimental aspects of immune function, such as autoimmune responses – where the immune system mistakenly targets endogenous molecules as if they were foreign – and hypersensitivity reactions.
Under Construction…
CURRICULUM VITAE
Michail A. Daniilidis MD, PhD.
Thessaloniki, 2024
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Professor of Internal Medicine/Clinical Immunology
Professor Emeritus at the Aristotle University of Thessaloniki
Michail A. Daniilidis, MD, PhD, has distinguished himself as a Professor of Internal Medicine and Clinical Immunology, and as a Professor Emeritus at Aristotle University in Thessaloniki, Greece.
Born in Thessaloniki, Hellas, he completed his high school education at the Experimental School of the University of Thessaloniki, before earning his Diploma in Medicine from the School of Medicine at Aristotle University of Thessaloniki. Following his graduation, Daniilidis fulfilled his military service obligations and subsequently served as a medical doctor in rural areas (mandatory service).
Daniilidis’s postgraduate journey commenced with his specialization in Internal Medicine, completed at the 2nd Internal Medicine Department of HIPPOCRATES Hospital, Aristotle University of Thessaloniki. He further specialized in Nephrology, achieved at the 2nd Nephrology Department of HIPPOKRATES Hospital, also under the auspices of Aristotle University of Thessaloniki.
His academic pursuits continued internationally, marked by his role as a Research Fellow at the Department of Transplantation Immunology, University of Heidelberg in 1984, and a visiting doctor at the Immunology Department of Univ. BICETRE Hospital in Paris, France, in 1990, a position funded by a scholarship from the Hellenic Society of Nephrology. Daniilidis returned to the University of Heidelberg as a Research Fellow in the Department of Transplantation Immunology in 1997 and later served as a Research Fellow at the Immunogenetics Institute of ULM University, Germany, in 2006.
His thesis, completed in 1988 at the Medical School of Aristotle University of Thessaloniki, focused on “The role of antigens and haplotypes of HLA D-DR locus in intrafamilial renal transplantation,” for which he received an excellent grade. Daniilidis’s career reflects a profound commitment to the advancement of medical science, particularly within the fields of internal medicine and clinical immunology, underscored by significant contributions to the understanding of immunology of reproduction, autoimmunity, immunogenetic diseases, and transplantation immunology.
Career at the Hellenic National Health System:
1985-1990: Internist at the National Health System (National Immunology and Histocompatibility dept, Hippocrates Hospital Thessaloniki)
Career at the Aristotle University of Thessaloniki (AUTH):
1990-1995: Lecturer of Internal Medicine-Clinical Immunology at the 1st Department of Internal Medicine, AHEPA Univ. Gen. Hospital, Thessaloniki, Greece.
1995-2001: Assistant Professor of Internal Medicine-Clinical Immunology at the 1st Department of Internal Medicine of the University of Thessaloniki (AHEPA Univ. Gen. Hospital, Thessaloniki, Greece).
2001-2007: Associate Professor of Internal Medicine/Clinical Immunology at the 1st Department of Internal Medicine of the University of Thessaloniki (AHEPA Univ. Hospital, Thessaloniki, Greece).
2007-2013: Professor of Internal Medicine/Clinical Immunology at the 1st Department of Internal Medicine of the University of Thessaloniki (AHEPA Univ. Hospital, Thessaloniki, Greece).
2013 September-2016 August: Director of the First Internal Medicine Clinic of the Aristotle University of Thessaloniki, University General Hospital AHEPA, Thessaloniki, Greece.
2016 September-2017 August: Professor of Internal Medicine/Clinical Immunology, Head of the Division of Clinical Immunology and Connective Tissue Diseases of the First Internal Medicine Clinic of the Aristotle University of Thessaloniki, University General Hospital AHEPA, Thessaloniki, Greece.
2017: Professor Emeritus at the Aristotle University of Thessaloniki
2018 – today: As an emeritus professor at AUTH, voluntary teaching of chapters of the course “CLINICAL IMMUNOLOGY” for the students of the Faculty of Medicine at AUTH.
Private Practice
1990 – today: Founder and director of “Immunological Research and Immunotherapy Centre“, the only Immunological centre founded by a professor of Clinical Immunology, with 30 years of experience and more than 3.000 successes (pregnancies and childbirths).
HONORS-AWARDS-SCHOLARSHIPS
–1986: Honorary distinction of the Medical Society of Thessaloniki for the successful organization and realization of the “first joint session of Medical Society of Thessaloniki and the Hellenic Society of Immunology” (December 4-6, 1986).
–1987: Prize for the work: “Cellular immunity in the acute phase of uveitis before the administration of treatment. Correlation with immunogenetic factors” from the Board of Directors of the Hellenic Ophthalmological Society (2nd Pan-Hellenic Ophthalmological Congress, Rhodes, 1987.
–1990: Scholarship of the Hellenic Society of Nephrology for the year 1990 (Department d’ Immunologie Cellulaire, Hopital BICETRE, Paris, France).
–1998: honorary letter of thanks from the medical students of the 3rd Pathology Clinic of AUTH (Director: Professor M. Holevas) for the contribution to the modernization and the implementation of a new educational program during their education (2/27/1998).
–2002: Honorary distinction for the work “Cytokine gene polymorphism in patients with inflammatory bowel disease” 22nd Panhellenic Congress of Gastroenterology, Athens, 21-24/11/2002.
–2004: First Prize of the Society of Military Medicine, at the 20th Armed Forces Medical Congress, for the paper “EBV-DNA in the peripheral blood and HLA class II typing in Greek patients with nasopharyngeal carcinoma”.
–2004: Award from the Board of the Hellenic Society of Immunology, for the successful organization of the 15th European Congress of Immunology (EFIS 2003).
–2014: Award for the contribution to the field of Reproduction (from the President of the Hellenic Society of Reproductive Medicine (June 2014, Thessaloniki, Inter-Balkan Medical Center).
–2017: Professor Emeritus at the Aristotle University of Thessaloniki
MEMBER OF SCIENTIFIC SOCIETIES:
-Hellenic Society of Immunology
-European Academy of Allergy and Clinical Immunology
-European Foundation for Immunogenetics
-European Society for Human Reproduction
-European Society for Reproductive Immunology (ESRI)
2002-2004: President of the Board of the Hellenic Society of Immunology.
JUNE 2003: President of the Organizing Committee of the 15th EFIS (European Federation of Immunological Societies) Rhodes, Greece.
MARCH 2017: Founder and Board member of the “Scientific Society for the STUDY of infection immunology” Thessaloniki, Greece.
SEPTEMBER 2017: Professor Emeritus of the Aristotle University of Thessaloniki
PUBLICATIONS:
-More than 200 publications (International and Hellenic Medical Press).
-Participation and/or collaboration in 38 Theses of the Faculty of Medicine, Aristotle University of Thessaloniki.
-Participation as an author in all the Editions of “CLINICAL IMMUNOLOGY”of the Faculty of Medicine, Aristotle University of Thessaloniki.
-Participation as an author in all the Editions of “INTERNAL MEDICINE” of the Faculty of Medicine, Aristotle University of Thessaloniki.
-Participation as an author in the first two Editions of “PATHOLOGICAL PHYSIOLOGY” of the Faculty of Medicine, Aristotle University of Thessaloniki.
RESEARCH FIELDS: Immunology of Reproduction and miscarriage Immunotherapy, Immunogenetics, Immunodeficiencies, Autoimmunity, Clinical Immunology and Allergy, Immunogenetics & Immunology of infectious diseases, Immunology & ENT diseases, Autoimmunity and Eye diseases, Transplantation Immunology.
CLINICAL TRIAL EXPERIENCE:
Participation at seven Clinical Trials (Research Committee, AUTh)
CONTACT:
TELEPHONE: +302310225325
Cell phone: 6944588038
Prof. Michail Daniilidis,
Ethnikis Antistasis 7B, Kalamaria, 55134 Thessaloniki, Greece
e-mail: mdaniilidis@gmail.com,
Secretariat: immunotherapycentre@gmail.com
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Founded
by the Professor of Internal Medicine – Immunology at Aristotle University of Thessaloniki, Michail Daniilidis.
Experience
30 years of experience in Clinical Immunology and Reproductive Immunology. 39 years in University Clinics
Diagnosis
Immunological causes of miscarriages and implantation disorders (unsuccessful embryo transfers). Immunogenetic predisposition to rheumatic diseases, autoimmunity, and allergies.
Successes
More than 3000 pregnancies and childbirths (successful diagnoses and treatments throughout Greece, Cyprus, and other countries).
Diagnosis of autoimmune and other immunological disorders, immunodeficiencies, etc.
Personalized Medicine
A different diagnostic and therapeutic approach for each couple and for each patient individually. The significant role of history, genetics, and specialized tests.
Laboratory - Collaborations
Specialized laboratory for Immunogenetics and immunological tests (PhD – reproductive immunology).
Permanent collaboration with a specialist hematologist and rheumatologist.
Πότε πρέπει ένα ζευγάρι να μας συμβουλευτεί
1. Εάν λαμβάνετε ανοσοθεραπεία χωρίς πλήρη ανοσολογική διερεύνηση
2. Δύο ή περισσότερες αποβολές πριν ανιχνευθεί καρδιακός παλμός (για παράδειγμα, βιοχημική εγκυμοσύνη ή κενός σάκος)
3. Οποιαδήποτε απώλεια κυήματος μετά τη διαπίστωση καρδιακού παλμού του εμβρύου (εκτός εάν ο έλεγχος έδειξε γενετική ανωμαλία)
4. Τουλάχιστον μία απώλεια κυήματος το οποίο έχει ελεγχθεί και βρέθηκε γενετικά φυσιολογικό
5. Αποτυχημένοι κύκλοι εξωσωματικής γονιμοποίησης παρά τη μεταφορά εμβρύων καλής ποιότητας
6. Οποιαδήποτε θνησιγένεια μετά από 20 εβδομάδες
7. ….
Αυτοανοσία και Αναπαραγωγή
Οι πτωχές αναπαραγωγικές επιδόσεις και ιδιαίτερα η εμφάνιση επαναλαμβανόμενων αποβολών κυήματος σε ορισμένες γυναίκες, είναι δυνατόν να αποτελούν το αρχικό σύμπτωμα αυτοανόσου νοσήματος (συστηματικός ερυθηματώδης λύκος, αυτοάνοση θυρεοειδίτις, κ.ά.). Κατά συνέπεια, η έγκαιρη διερεύνηση των ανοσολογικών αιτίων των αποβολών είναι δυνατόν να έχει καθοριστική σημασία όχι μόνον για την επιδιωκόμενη τεκνοποίηση, αλλά και για την υγεία της υποψήφιας μητέρας.
Διάγνωση των επανειλημμένων αποβολών (ΕΑ)
Βασική προϋπόθεση προκειμένου να πραγματοποιηθεί ο εργαστηριακός ανοσολογικός και ανοσογενετικός έλεγχος σε περιπτώσεις αποβολών, αποτελεί η προηγούμενη ολοκλήρωση του ελέγχου για τον αποκλεισμό των γυναικολογικών, χρωμοσωμικών-γενετικών, ενδοκρινολογικών αιτίων και ορισμένων λοιμώξεων.
IMMUNOTHERAPY CENTRE
Thessaloniki, Greece